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1,2,4-Triazole derivatives and their activity


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  • Product Description

1. All the 1,2,4-triazole derivatives prepared are pro-drugs since all have -N-C=O or -N-C=S links, which are enzymatically degradable, thus releasing both i.e. 1,2,4-triazole and the ligand at the target site. 2. The conjugate of curcumin with triazole has been found to be a more potent antifungal and antibacterial reagent. Further in vitro and in vivo experiments can be carried out. 3. 1,2,4-triazole dervative of isoproturon has been found to be most effective herbicide which could be used as a substitute of isoproturon. Further field trials are required. 4. The observed enhanced activity of all these synthetic compounds may be due to their combined effect at the receptor, producing synergism. 5. However, the validation of this synergistic effect needs further work. 6. The results have opened a new approach for designing novel and more effective pro-drugs.

Product Specifications
SKU :COC40501
AuthorKuruba Adeppa and Krishna Misra
Number of Pages196
Publishing Year4/22/2012
Edition1 st
Book TypeOrganic chemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-02-08 00:00:00
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