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1-Amino-2-phenylethane derived sulfonamides


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  • Product Description

The presented study encompasses the synthesis of a series of sulfonamides derivatives of 1-amino-2-phenylethane in excellent yield by reaction with various aryl sulfonyl chlorides, in the presence of aqueous sodium carbonate solution under dynamic pH control. These projected structures of the synthesized derivatives were characterized by IR, 1H-NMR and EIMS spectral techniques. Moreover, the screening of derivatives against acetyl cholinesterase (AChE), butyryl cholinesterase (BChE) and lipoxygenase (LOX) enzymes rendered these molecules as potent inhibitors of cholinesterase enzymes, relative to Baicalein and Eserine, which were used as reference standard.

Product Specifications
SKU :COC61145
AuthorMuhammad Athar Abbasi and Sabahat Zahra Siddiqui
Number of Pages60
Publishing Year16.09.2014
Edition1 st
Book TypeChemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00
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