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A Novel Bioreactor for Tissue Engineering


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Current research in tissue engineering indicates the need to investigate the effects of mechanical and hydrodynamic forces on the development of engineered-tissues cultivated in bioreactors. The unique geometry of the wavy-walled bioreactor provided various flow environments for tissue cultivation and the elucidation of cause-and-effect relationships between hydrodynamic parameters and tissue properties. These studies revealed that shear stress, as well as axial and radial flow affected tissue size, spatial distribution of cells within the scaffolds, and formation of a dedifferentiated layer of chondrocytes around tissue. A kinetic tissue-growth model was developed that predicts chondrocyte proliferation and extracellular matrix deposition in constructs cultivated in bioreactors. Using artificial neural network models, these kinetic constants were correlated with the hydrodynamic parameters. Finally, a dynamic optimization tool was developed in order to predict the bioreactor operating conditions and hydrodynamic parameters that yield tissues with desired properties.

Product Specifications
SKU :COC83483
AuthorBahar Bilgen
Number of Pages280
Publishing Year2011-06-28T00:00:00.000
Edition1 st
Book TypeAerospace & aviation technology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00