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A Theory of Calcium Dynamics in Paralyzed Human Soleus

 

Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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  • Product Description
 

In current models of muscle force and fatigue in denervated subjects, the mechanistic understanding of the role of baseline calcium current (R0) and the voltage sensitivity (km) is inadequate. R0 and km are assumed to be scalar, which generates errors in predicting force and fatigue respectively in response to external electrical stimulation. Previous work generated experimental data that conform to the Riccati/logistic/Boltzmann equation. To extend that work, a theoretical analysis of the role of calcium current, assumed to be a Riccati-Bass growth/diffusion/decay process, is presented for fresh and fatigued paralyzed muscle. The analysis will be included in existing models of muscle force and fatigue to determine any change in predictive accuracy. An improved theoretical biophysical model of the calcium current will lead to better understanding of muscle dynamics in paralyzed subjects so that electrotherapeutic stress injuries from overstimulation may be prevented.

Product Specifications
SKU :COC43575
AuthorM.J. Conaway
LanguageEnglish
BindingPaperback
Number of Pages348
Publishing Year2010-11-29T00:00:00.000
ISBN978-3639314601
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-01-08 00:00:00
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