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ADAM12 in tumor progression


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Cancer is a highly complex disease involving many different cellular processes, including cell proliferation and cell adhesion. ADAM12 - a disintegrin and metalloprotease, which is found upregulated in various cancer types, has been implicated in these processes. In this book, immortalized primary tumor cell lines from a breast cancer mouse model was generated and utilized to investigate the role of ADAM12 in tumor progression. This study identified ADAM12 to function in the tumor cells rather than the stromal cells of the tumor microinvironment to promote tumor progression. Additionally the adhesion domains of this multifunctional protein might play a crucial role in tumor progression. In conclusion, the overall function of ADAM12 should be seen in the broader context of the different functional domains and the microinvironment in which it acts.

Product Specifications
SKU :COC76660
AuthorCamilla Nehammer
Number of Pages80
Publishing Year2014-04-25T00:00:00.000
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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