The impact of Human Immune Deficiency/Acquired Immuno-Deficiency Syndrome (HIV/AIDS) is evident in the rising numbers of those orphaned by HIV/AIDS. Apart from death, millions of children live in households with sick and dying members. These Orphans and Vulnerable Children (OVCs) affected by HIV/AIDS are stigmatized, isolated, discriminated against, disinherited and often deprived of basic education and care. This study was carried out in Kadibo Division, Kisumu District. Systematic random sampling was used. The sampling frame consisted of all the households with OVCs supported by various Community Based Organizations (CBOs) . A total of 111 households were interviewed and nutritional assessment for 322 children was done. The study was designed to assist CBOs improve their effectiveness in provision of optimal nutritional care for OVCs. Data collection applied both quantitative and qualitative methods. Pearson?s product correlation moment was applied to determine the strength of association between independent and dependent variables. Probit regression model was developed from the independent and dependent dichotomous variables.