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Anticarcinogenic activity of Clerodendrum serratum in albino mice

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Skin, a major environmental interface for the body, is accidentally or occupationally exposed to a number of chemical mutagens and carcinogens. Skin cancer accounts for 30% of all diagnosed cancers in the world. The evaluation of anticarcinogenic activity of Clerodendrum serratum leaf extract on DMBA induced skin carcinogenesis in swiss albino mice revealed that there was decrease in the body and organs weight, affected biochemical contents, dehydrogenases and phosphatases activities and oxidative stress parameters of liver, kidney and testes of mice. Amelioration in the above mentioned parameters was observed on treatment with methanolic leaf extract of Clerodendrum serratum, indicating its anticarcinogenic potential. The inferences drawn from the study revealed that the methanolic leaf extract of Clerodendrum serratum recovered the biochemical contents, dehydrogenases and phosphatases activity and oxidative stress parameters of liver, kidney and testes of mice. The presence of major chemical components such as phenolics, steroids, diterpenes and triterpenes, flavonoids and volatile oils attributed its chemopreventive potential as an antioxidant and antiproliferative agent........

Product Specifications
SKU :COC61057
AuthorJayaraj Chinchali and Basappa Kaliwal
LanguageEnglish
BindingPaperback
Number of Pages152
Publishing Year20.11.2014
ISBN9783659640858
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00
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