Till now, human still relies on plants for a variety of health problems in spite of the availability of synthetic drugs in therapy. Numerous plants have been used as folk medicine in diabetes treatment. In view of the existing hypoglycemic agents develop adverse effects, and global diabetes burden is estimated to rise from about 118 million in 1995 to 220 and 300 million people in 2010 and 2025 respectively, many researchers are actively seeking medicinal plants as the alternative biotherapeutic sources. The present monograph provides a quick and comprehensive review of 200 antidiabetic medicinal plants for researchers, industrialists, academicians, herbalists and general public. Information on common name, synonym, geographical distribution, parts used, potential active substance, effective dosage, mode of delivery, adverse effect and pharmacodynamic action of plants are summarized from scientific literatures and clinical studies. These monographs provide an excellent outline of herbs for future development into drugs and/or formulated into functional dosage forms.