Anxiety and depression have been reported to be quite common after a myocardial infarction. These symptoms have been associated with increased mortality and overall poorer outcomes. Studies worldwide have attempted to estimate the prevalence of depression and anxiety in patients with myocardial infarction. Research from the developing world has been sparse in this regard. This work established that anxiety and depression are quite common after a myocardial infarction in the Indian population. Relationship of these symptoms with a wide variety of clinical parameters have been assessed in this study. Symptoms of anxiety and depression have a likelihood of being missed in a busy outpatient service. Proper assessment and management of these symptoms can improve clinical outcome and quality of life of patients.