This book is a humble endeavor to make the new learners understand the vastness of Philosophical approach of Buddhism. This book is a simplified version and provides guidance on how to apply the Buddhist concept of emptiness in modern science. This is the first episode in this series which basically deals with the emptiness of matter in perspective of Applied Buddhism. "Applied Buddhism" is the foundation of our true understanding of all the events occurring in nature. The term "Applied Buddhism" explains how every person can relate Buddhist ideas in his or her daily life and in profession. However, many people even today, are unaware of the fact that modern science has its long history of origin which can be traced back far from the Buddhist era.