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  • Product Description

Arthritis is a disease in which there is inflammation of one/more joints , which results in pain,swelling , stiffness and limited movement ,redness,warmth around the joint.Rheumatoid arthritis comes under the category of autoimmune disease and various genes and corresponding proteins seem to cause the disease on mutation and altered/increased function of basically degrading cartilage,collagens,laminin,fibronectin etc. In this book, an effort has been made to analyze and detect the mutationally hot spot region (specific amino acid –asparagine ;position-465)in the overlapping region from domain,binding site and disorder regions of the MMP1 protein(chosen after analyzing the roles and functions of the entire MMP family) by using various tools and softwares and to thus target and inhibit the same by docking suitable compound (searched and optimized) via in Silico drug design approach(Structure based) thus helping in the cure of Arthritis.

Product Specifications
SKU :COC36462
AuthorAshish Kumar Rai and Rohit Raj Singh
Number of Pages240
Publishing Year2012-07-07T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00