An attempt has been made in the present investigations to study the quality of underground well/tube well water samples and their interrelationship between different ions which are present in irrigation water. About 84 underground water samples were collected from representative areas of Bechraji, Mehsana,Kadi and Vijapur Talukas of Mehsana district. Irrigation water samples were analyzed for Electrical Conductivity (EC), pH, Total Dissolved Solids (TDS), cations (Ca+2, Mg+2, Na+and K+) and anions (CO3-2, HCO3-1, Cl-1, and SO4-2). Various indices viz.,Residual Sodium Carbonate (RSC), Sodium Adsorption Ratio (SAR) and Soluble Sodium Percentage (SSP) were calculated from the estimated cations and anions expressed in me/L. In general, the well/tube well water samples of Mehsana district were slightly alkaline in reaction (pHvalues 7.02 to 8.21), TDS values range from 270 to 1970 ppmin study area. The maximum salt concentration was found in groundwater samples of Bechraji and Mehsana taluka and the minimum in groundwater samples of Kadi and Vijapur taluka. Statistical analysis done by Dr. Kamlesh A. Patel.