Atarax Anti Itch Lotion is a topical lotion containing a calamine base with Aloe Vera Gel and Pramoxine Hydrocloride. Tetrahydrocurcmin, a powerful anti-oxidant, is also a part of the formulation. The pH of the lotion is near neural and thus safe to use to help protect various types of Pruritis including peri-anal Pruritis which also includes Pruritis caused by Hemorrhoids.