Atherosclerosis (Salabate Sharaeen) is one of the commonest and most prevalent diseases of the world, its underlying pathologic process causes several cardiovascular and cerebrovascular complications. It is a well known fact that Hyperlipidaemia and Obesity are important risk factors for Atherosclerosis. Unfortunately, there is no convincing treatment available for the management of atherosclerosis in Modern system of Medicine. Therefore, search of safe and effective drug for its management is quite necessary. In Unani system of medicine, Habbe Aftimoon is being used for the management of various Amraze balghamia and saudawia, which include Salabate Sharaeen too, therefore this drug may prove useful in this condition.