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Azole Derivatives as an Protein Tyrosin Kinase Inhibitors


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

In the present book “The Azoles Derivatives as Potent Protein Tyrosine Kinase Inhibitor”, we provide an exhaustive literature regarding the Antiproliferative potential of Protein Tyrosine Kinase Inhibitors. Various analogous of imatinib were Designed and prepared by replacing the pyrimidine ring of imatinib with an azole nucleous like Imidazole, Benzimidazole and Benzthiazole. Imatinib an well reputed anti-cancer agent contain pyrimidine ring, composition of various biological enzymes and proteins of normal cell, as analogous of ATP inhibit the natural cell protein Kinase, hence responsible for non-specificity in activity with low selectivity and side effects. BMS-33197 an excellent Bcr-Abl kinase inhibitor contain an oxazole nucleolus responsible for its activity so various imatinib analogous were prepared isosterically.

Product Specifications
SKU :COC31566
AuthorYogesh Agrawal and Mona Agrawal
Number of Pages84
Publishing Year10/23/2012
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00