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Benzimidazole-2-carboxylic acids

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Rheumatoid arthritis is progressive, autoimmune inflammatory chronic disorder which do not have curative treatment yet. Aryl and hetero-aryl acids has maximum share of anti-inflammatory drugs in the therapeutics today as non steroidal anti-inflammatory drugs (NSAIDs). Benzimidazole moiety with heteroaryl and psudoacedic nature is promising moiety for development of NSAIDs. In the present project, synthesis, pharmacological evaluation, probable mechanism of action and quantitative structure-activity relationship (QSAR) of benzmidazole-2-carboxylic acids are reported. The excellent efficacy and safety was observed for benzimidaxole-2-carboxylic acid derivatives in laboratory animal models of inflammation and rheumatoid arthritis without side-effect of gastrointestinal disturbances. The reliving effects against pain and fever in experimental animal models suggested promise as potential NSAID.

Product Specifications
SKU :COC32904
AuthorPrasad Thakurdesai,S.G. Wadodkar and C.T. Chopde
LanguageEnglish
BindingPaperback
Number of Pages124
Publishing Year10/31/2010
ISBN978-3843372367
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00