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Benzothiazole – A Biologically Important Scaffold

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Development in biological evaluation of heterocyclic molecules has undergone manifold changes and the advancement in molecular biology has eased the design of new molecules based on their mechanism of action. Proposed work is based upon the development of newer analogues of benzothiazoles followed by their biological evaluation. Benzothiazoles have been reported with good biological activities ranging from antiparasitic, anti-inflammatory, antitumour, p56lck inhibition, immunosuppressive antitubercular activity etc. The derivatives of benzothiazoles have been developed very recently, targeting antitumour activity by various workers. The type of molecules are reported to act based upon their interaction with aryl hydrocarbon receptor as well as their interaction with p56lck. Reports are available mentioning the importance of metabolism and the deactivation of the molecules with respect to their biopotency.This gives an additional avenue for the researchers to work upon the concept of prodrug and mutual prodrugs of these bioactive molecules and come up with better activity profile. With this background, we thought to develop newer analogues of the nucleus benzothiazole.

Product Specifications
SKU :COC53040
AuthorPadmavathi P. Prabhu,C. S. Shastry and Theivendren Panneer Selvam
LanguageEnglish
BindingPaperback
Number of Pages192
Publishing Year2014-02-07T00:00:00.000
ISBN9783659523328
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-06-08 00:00:00
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