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Bilayer tablet of Metoprolol tartrate and Hydrochlorthiazide

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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Rs. 3,651

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  • Product Description
 

The main goal of present study was to formulate and invitro evaluate bilayer tablets of Metoprolol tartrate and Hydrochlorothiazide. In this tablet hydrochlorothiazide was formulated as immediate release for which sodium starch glycolate and croscarmellose sodium was used as superdisintegrants. While metoprolol tartrate was formulated as sustained release for which HPMC K4 M and Eudragit RSPO were used as release retarding polymers. In this bilayer tablet hydrochlorothiazide showed quick action and the sustained release of metoprolol tartrate maintain the drug concentration within therapeutic range for period of 12 hrs. Prepared tablets were evaluated for thickness, hardness, friability, uniformity of weight, disintegration time and dissolution study. Disintegration time and drug release were taken as the basis to optimize the tablets.

Product Specifications
SKU :COC31457
AuthorUttam Nalawade,Ratnadeep Ghadage and Shrinivas Mohite
LanguageEnglish
BindingPaperback
Number of Pages120
Publishing Year8/19/2012
ISBN978-3659186684
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00