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Biofilm Formation and Antimicrobial Resistance

 

Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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  • Product Description
 

This study investigated antimicrobial susceptibilities of clinical CoNS isolates in different stages of the biofilm formation process. Planktonic cells exhibited similar susceptibilities in comparison with early adherent monolayers. A mature biofilm showed similar resistance to antimicrobial eradication to planktonic cells at stationary phase. In order to investigate mechanisms of high resistance of biofilms to various antimicrobial agents, the percentages of tolerant- but-killable cells and non-killable persister cells in different bacterial populations were examined. More tolerant-but-killable cells were found in biofilms than in planktonic cultures at log phase. Persister cells were only present in biofilms, not planktonic cultures. Further study showed that ability of CoNS to adhere to polymer surfaces and grow into a highly dense mode, rather than their ability to build up biofilm matrix, contributed to their high resistance to antimicrobial agents. Finally, different agents were tested as catheter lock solutions. Ethanol was found to be superior to most antimicrobial agents in eradication of biofilm cells.

Product Specifications
SKU :COC38537
AuthorYue Qu and Margaret Deighton
LanguageEnglish
BindingPaperback
Number of Pages220
Publishing Year10/15/2010
ISBN978-3639299397
Edition1 st
Book TypeMicrobiology (non-medical)
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00