1, 3, 4-Oxadiazole are heterocyclic compounds containing one oxygen & two nitrogen atom in a five membered ring. 1,3,4-oxadiazole derivatives have to placed a major role in the pharmaceutical chemistry .The number of so many synthetic compounds with oxadiazole nucleus used for antibacterial ,antifungal , analgesic and anti-inflammatory activities .Derivatives of 1,3,4-oxadiazole with suitable substitution at 2,5 – position have been already reported to possible biological activities . 1,3,4-oxadiazole derivatives act as anticonvulsant & diuretics. These observation and our interest in the pharmaceutical chemistry of heterocyclic compounds promoted us,we have synthesized different derivatives of,1,3,4-oxadiazole with different substituent at 2&5-position . These derivatives have been also screened for their anti-inflammatory activity.Mostly five membered aromatic system having three heteroatom’s at symmetrical position have been studied because of their physiological properties.It is also well established that various derivatives of 1,3,4-oxadiazole exhibit broad spectrum of pharmacological properties such as antibacterial and anti-fungal activities.
|Author||Arvind kumar singh and R. Parthasarthy|
|Number of Pages||56|
|Country of Manufacture||India|
|Product Brand||LAP LAMBERT Academic Publishing|
|Product Packaging Info||Box|
|In The Box||1 Piece|
|Product First Available On ClickOnCare.com||2015-02-08 00:00:00|