Apolipoproteins B/A1 are protein components of antherogenic and non antherogenicparticles. At the moment, measurement of LDL and HDL in various combinations is in practice for diagnosis of atherosclerotic CAD. But studies have proved that measurement of their protein components is much better, cost effective, error free and standardize. the current cross sectional analytical study has confirmed that Apo B/A1 ratio is much better biochemical indicator and people with obesity, high hip to waist ratio and other known risk factors for CAD can be better identified for future risk of CAD by measuring their Apo B/A1 ratio specially in men, however value 1.8 rather than 0.9 can be more useful. Therefore all old age men with known risk factor must immediately be monitored and given lipid lowering drugs for prevention of developing CAD.