Mycobacterium bovis is significant Zoonoses that can spread through aerosols and by ingestion of raw milk. Research was conducted to find out the cases of bovine tuberculosis in 50 animals reared by 25 tuberculosis (TB) infected persons that are getting the Directly Observation Treatment for Shorts coarse (DOTS) at Kavre District of Nepal. The intradermal cervical tuberculin test was followed to identify the bovine tuberculosis by injecting 0.1 ml of tuberculin antigen from Canadian Food Agency and measuring the increase in thickness after 48 and 72 hours. Results was taken to be negative if the change in thickness waless than 2.0 mm.The thickness remain the same in 45 animals (90%) and 5 animals (10%) were positive for tuberculin having the change in skin thickness. Similarly among the 25 tuberculosis inhousehold, 13(52%) had an extra pulmonary type of TB and 12(48%) had pulmonary type of TB. Animals were also higher infected (60%) in household where their owner had extra pulmonary type of TB. Overall prevalence of TB in human where their animal was infected with BTB in our study area was 20%.