Brucellosis, worldwide the most important zoonosis and remains a major health problem. This bacterial pathogen is also classified by the Centers for Disease Control and Prevention (CDC) as a category (B) pathogen that has the potential for development as a bioweapon. After tuberculosis, brucellosis is the most important bacterial disease of livestock in Bangladesh. There are sporadic reports of prevalence of brucellosis in cattle, goats, sheep, buffalo and including human. Detailed epidemiological studies are essential to design an appropriate control strategy for the disease. The book, therefore, illustrates the true prevalence, distribution and risk factors of brucellosis, guidelines and methods of isolation and characterization of Brucella spp. from infecting ruminants. The exciting new study shows a new way of developing the livestock and public health policy of government as well as professionals, prevention and control of brucellosis nationally and at international level to improve livelihoods. On other hand anyone else who have interest on the epidemiology of brucellosis.