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Butenolide: A Novel Synthesis and Biological Activities

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The primary role of medicinal chemist has become one of improving upon existing drugs by increasing their potency and duration of action and by decreasing toxic side effects as well as creating new drugs by molecular modifications. Very useful synthetic analogue with improved therapeutic properties can be obtained from a single lead compound by structural modification. The same applies to the group of natural lactone of plant origin, one of the diverse and important system of natural products with a broad spectrum biological activities. Physiological activity of natural lactone is known ever since santonine was used as anthelmintic and ascarisidal agent. The biological importance of unsaturated lactone is well known. The butenolide system is present in many cardiac glycosides shows strong cardiotonic activity. In particular, the ?-alkylidene butenolide skeleton is a useful entity that is present natural products such as fibrolides, dihydroxerulin and protoanemonin. Protoanemonin and its analogues possess antiviral, antibiotic and anticancer activities.

Product Specifications
SKU :COC31369
AuthorARVIND KUMAR,Vaishali Singh and Sourav Ghosh
LanguageEnglish
BindingPaperback
Number of Pages64
Publishing Year5/28/2012
ISBN978-3659132667
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00