This study strongly suggests that practical work has the capacity to enhance science education in Uganda. Despite practical works’ limitations as a pedagogical strategy, its merit bolsters the understanding of the nature of science. However, no stand-alone ‘method of instruction’can foster the understanding of the nature of science and by extension ensure a solid science education. Therefore, practical work needs to be complemented by other pedagogical methods such as ‘argumentation’, ‘science beyond the classroom’–out-door learning of science, study of the philosophy and history of science (among others). In brief, to realise the goal of science education in Uganda(i.e. science literacy)the use of practical work and other pedagogical strategies are important to help the learners understand the nature of science which would bring about fostering of science education.