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Cell Cycle Control of Mammalian Neural Stem Cells


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

The potential to unlimitedly expand and generate differentiated cell types is a key feature of somatic stem cells. Within the nervous system, cellular and environmental determinants tightly control the expansion and differentiation of neural stem cells. Importantly, a number of studies indicate that changes in cell cycle length can influence development and physiopathology of the nervous system, and may have played a role during evolution of the mammalian brain. Specifically, it has been suggested that the length of G1 can directly influence the differentiation of neural precursors. This has prompted the proposal of a model to explain how manipulation of G1 length can be used to expand neural stem cells. If validated in non-neural systems, this model may provide the means to control the proliferation vs. differentiation of somatic stem cells, which will represent a significant advance in the field.

Product Specifications
SKU :COC28480
AuthorFederico Calegari and Paolo Salomoni
Number of Pages68
Publishing Year2010-05-07T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-29 00:00:00