This book review the synthetic approaches used for the synthesis of isocyanates and ureas. Ureas is a group of chemical compounds, structurally contain R'RN-CO-NRR' functional group consist of carbonyl group sandwiched between two moieties of organic amine. Allantoin, hydantoin and carbamide peroxide are a few examples of ureas compounds. The compounds of ureas are strongly related to biuret and on the basis of their structure they are highly correlated to amides, diimides, carbamates, thiocarbamides and carbiimides. The detailed discussion of synthesis of isocyanate and ureas with chemical structure and schemes enhance the understanding of reader. The book also highlights the biological importance of ureas and its derivatives. With detailed studies that not only illustrate the synthetic methodologies but also focus on the pharmacological and medicinal importance of nitrogen containing compounds, this book is a practical, hands-on reference for upper-level undergraduates and graduates students and researchers in the field of medicinal chemistry.