My book entitled “Chemoenzymatic synthesis of biologically active entities, synthesis of both the stereoisomers of dihydrokawain-5-ol and development of novel synthetic methodologies”. This has been divided into four chapters. Chapter-I is Biotransformations Introduction and Background Information. Chapter-II to IV are Chemoenzymatic synthesis of enantiomerically enriched Umbelactones, (R)-GABOB and (R)-Carnitine, (-)-Centrolobine, (R) and (S) enantiomers of Timolol, Kawalactones. This also include enantioselective total synthesis of both the stereoisomers of Dihydrokawain-5-ol and Cu(BF4)2•xH2O catalyzed one-pot synthesis of 'Biginelli' and 'Strecker' reactions.