Agriculture is one of the most vulnerable sector to Climate Change impact. The impact is even stronger in Mountain region of Nepal; where the topography is fragile and agriculture is important for the daily subsistence. It is crucial to increase the understanding of the actual Climate Change dynamics on agricultural activities at the household level in Mountain region. This book is based on the research which examines the local climatic trends and its impacts, vulnerability and adaptation of the agriculture sector in the Mountain Region of western Nepal. The study shows that Agriculture sectors of Mountain region of Nepal has been severely affected by the Climate Change impacts and local farmers lack adaptation measures. The existing local and institutional strategies are not sufficient and sustainable to cope with climatic vagaries. It is very important to address the problems in this region with institutional support and through a long-term policy perspective.