The emerging global scenario offers immense opportunities and challenges. Only those nations can be benefited from it which has acquired the required knowledge base and skills. Every country which has sound and quality education system, can meet the challenges and can exploit the opportunities. Pakistan is facing serious challenges in its education system, specifically in its primary education. The enrollment at this level is quite low and confronting with a severe threat of dropout. Only one out of 3 boys and only one out of 05 girls, enrolled in the first grade, completing their primary education. It greatly affects enrolment at the higher levels i.e. at tertiary level it is even lower than 5%. Therefore, it is necessary to come with a comparative picture of dropout factors with respect to genders and also to give some comparative inputs for decision making in education in Pakistan.