Traditional bonding materials are incapable of bonding in presence of moisture, are challenged by “Moist-field” bonding materials. Claims and counter claims are made regarding their, efficacy to use as ideal orthodontic bonding adhesives. Present study done to compare Shearbondstrength of Ethyl cyanoacrylate(Smart Bond) and self cure acrylic(Rely-a-Bond) under different conditions. Rely-a-Bond and Smart Bond, are acceptable bonding materials in dry and wet conditions respectively with regards to Shear bond strength values per se. Rely-a-Bond showed significant increase in Shear bond strength from 1 hour to 24 hours. Smart Bond shows significant decrease in Shear bond strength over time. Rely-a-Bond has significantly increased Shear bond strength than Smart Bond at all times. Rely-a-Bond has high probability of failure at 1 hour; however show drastic improvement at 24 hours. Hence usage of Rely-a-Bond, force application should be deferred for 24 hours. Smart Bond adhesive is unsuitable for use as a bonding agent in routine orthodontic practice. However, the ability of this adhesive to adhere to wet surfaces could enable practitioners to bond attachments in wet conditions.