Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

Conformation and Stability Of Mixed DNA Triplex

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 

Check Your Delivery Options

 
Rs. 5,208

Availability: In stock

 
  • Product Description
 

DNA triple helices are formed by the binding of a third strand oligomer in the major groove of a Watson -Crick (WC) duplex. Interest in triple-helical nucleic acids-that is, triplex has been stimulated by the recognition of their potential biological roles and genetic applications. Although direct evidence of participation of triplexes in biological processes has not yet been obtained, there are ample data to suggest that triplexes can be involved in regulation of DNA replication, transcription, recombination and development.During DNA triplex formation third oligonucleotide strands binds with purine rich strand in major groove of DNA through Hoogsteen bindings. Third strands may be parallel or antiparallel to first strand. A further extension of this model is given for mixed-base-sequences in which third strand recognizes both the strands of DNA duplex through H-bonding (Mixed DNA triplex). In this manuscript a systematic study on the conformation and stability of mixed DNA triplexes and their possible structure in solution and in vacuum using computational techniques has been described. Which may be important for researchers and new comers.

Product Specifications
SKU :COC60947
AuthorRakesh Kumar Tiwari and Rajendra Prasad Ojha
LanguageEnglish
BindingPaperback
Number of Pages220
Publishing Year04.08.2014
ISBN9783659478123
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-08-05 00:00:00