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Connexin 43 (Cx43) Expression in Human Colorectal Cancer


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

Connexins constitutes a family of structurally related transmembrane proteins that connect two adjacent cells by forming gap junctions. Connexins are multi- functional proteins with diverse role in the cell physiology. Connexin 43 is an important gap junction protein in vertebrates and is known for its tumor suppressive properties. Connexin 43 plays an important role in the regulation of cell growth, differentiation and is important for maintainance of tissue homeostasis. Cx43 is abundantly expressed in the human intestinal epithelial cells and muscularis mucosae. Therefore, loss of Cx43 protein may be associated with a role of this protein in the carcinogenic process of colorectal cancer. The down regulation of Cx43 expression in the human colorectal strongly supports the role of this protein in regulating cell growth. It provide a significant insight about the tumor suppressive properties of the Cx43 and its potential as a diagnostic marker for detecting colorectal cancer.

Product Specifications
SKU :COC87080
AuthorRehana Ismail and Mahboob Ul-Hussain
Number of Pages80
Publishing Year2013-12-20T00:00:00.000
Edition1 st
Book TypeBiophysics
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00