The livelihood East Amhara subregion is dependant on rainfed agriculture however, erratic nature of the rainfall distribution over this area greatly affects the crop production. The climate change model manipulated for this work projects temperature is likely to increase while precipitation tends to decrease. The model simulation result for seasonal variability and crop calendar over SEA and CEA revealed that the onsets and offsets of the growing season''s lies within the months of June and November and NEA will have only eleven years of growing season for the coming 30 years 2009 to 2038. This book therefore explores climate change and climate variability under climate change scenarios for this cenutry based on rainfall,soil moisture and temperature. Moreover, the appropriate crop calendar developed for the coming 30 years in accordance to the climatic changes and short-term extremes could enable to address drought and famine problem while enhancing food security over the area. This work also contributes towards the early warning system so that it enables to mitigate future disasters due to climate variability, extremes and change.