This book has a direct aim to explain you with the whole idea of dendrimer and cyclodextrin. Dendrimers containing cyclodextrin exhibited that the ?-CD-grafted biodegradable dendrimers is a potential candidate as an efficient drug carrier systems due to its relative stability in aqueous solution and its drug encapsulation and release properties. Cyclodextrins and their complexes constitute a fascinating subject that, due to its complexity and specific chemical structure. This great attention makes today’s CD science and technology extremely involved in a large number of important areas of research covering both basic and applied science in chemistry and biology. Their ability to modify the behavior of trapped guests is being used for example, in chemistry, biology, food, pharmacy/medicine and agriculture. This book is mainly focused on the properties and uses of dendrimers, cyclodextrins, and application of dendrimer-modified cyclodextrin. Also, this book reflects the height of the latest knowledge of these sweet nanocavities to host different kinds of guests on the drug delivery systems.