Metabolic syndrome is associated with other risk factors and is associated with cardiovascular disease. Obesity is a risk factor for chronic kidney disease (CKD) . Perception mechanisms linking obesity and chronic kidney disease are important not only of the social health burden of both conditions, but also, due to novel insights into the underlying mechanisms may lead to new strategies to treat or prevent chronic kidney disease and its associated comorbidities. More developed countries are facing an obesity epidemic and growing.experience rapid increase in the prevalence because this age group experienced the greatest burden of chronic kidney disease (CKD), and cardiovascular disease, malignancy, that each of them may be aggravated with obesity. Obesity is almost certainly indirectly contributes to chronic kidney disease due to associates with many major CKD risk factors such as diabetes, high blood pressure, and atherosclerosis. Cystatin C has recently been shown as an accurate indicator of glomerular filtration rate with benefits than serum creatinine . Glomerular filtration rate is the best overall index of renal function in health and disease.