This work developed an integrated transient daylighting and energy model to study the effect of façade design options on building energy consumption and occupant comfort. Full-scale experiments were conducted in controllable and reconfigurable facilities to measure real comparison and savings of different façade design and control options as well as to validate the developed model. Innovative shading controls were developed for maximizing daylight utilization and minimizing energy consumption. Extensive studies were presented for different orientations, window sizes, glazing types, shading properties and controls and locations. Uncertainty and sensitivity analysis were also performed revealing that shading control strategy, window size and glazing properties are the most important factors affecting building energy consumption.