The present study focused on women''s psychological health. It explored the relationship between depression and quality of life using two main research paradigms – the quantitative (survey method) and the qualitative (focus group discussion). Women''s quality of life was affected by geographical, social¸ cultural, economical, environmental, political and health related factors. The study focused on samples of women from the general population and Psychiatry outpatients to examine differences with respect to these critical issues. Depression was defined in cultural terms and efforts were made by the researcher to understand how women coped with it.