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Design And Development of Alfuzosin HCL Floating Microspheres

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

The purpose was to formulate Floating microspheres of Alfuzosin HCl, an orally administered alpha adrenergic blocker used to treat benign prostatic hyperplasia with a view of improving its oral bioavailability and giving a prolonged release of drug.Floating microspheres with biocompatible enteric acrylic polymer such as Eudragit S100 and cellulose polymers such as HPMC K100 M were successfully prepared by emulsion solvent evaporation method. The particle size analysis revealed that the size of microspheres was found to increase with increase in the concentration of polymer.. In vitro drug release studies showed that the release of drug decreases with increases drug to polymer ration of microspheres. . From the stability study it was found that there was no significant change in the physical appearance, drug entrapment, release characteristics and floating behavior of the microspheres.

Product Specifications
SKU :COC85168
AuthorMegha Shah and Mukesh R. Patel
LanguageEnglish
BindingPaperback
Number of Pages184
Publishing Year2013-09-13T00:00:00.000
ISBN9783659427886
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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