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Design and evaluation of prolonged release gliclazide matrix tablets


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

In the present study an attempt has been made to evaluate the effect of hydrophilic polymers on the release profile of drug from matrix system. Matrix tablets of Gliclazide were prepared by both direct compression and wet granulation process using METHOCEL K15M CR, METHOCEL K4M CR, METHOCEL E4M CR and HYPROMELLOSE 15cps.Release kinetics of Gliclazide from these extended release matrices at Phosphate buffer (pH 7.4) using USP paddle method was conducted for 10 hours and examined. Statistically significant differences were found among the drug release profile from different classes of polymeric matrices, polymer concentration and granulation process.

Product Specifications
SKU :COC30967
AuthorTanbir Ahammad and Saki Sultana
Number of Pages276
Publishing Year2012-04-06T00:00:00.000
Edition1 st
Book TypePharmacology
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00