Call Us 080-41656200 (Mon-Sat: 10AM-8PM)
Free Shipping above Rs. 1499
Cash On Delivery*

Design of β-peptide foldamers by stereochemistry and topology

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
Delivery in :  10-12 Business Days

 

Check Your Delivery Options

 
Rs. 1,781

Availability: In stock

 
  • Product Description
 

Novel β-peptidic secondary structures have been gained with five and six membered alicyclic side-chains. We analyzed various secondary structures of different foldameric and α-peptidic structures as a function of the back-bone stereochemical pattern. The results showed that the homochiral and the alternating heterochiral systems do not cover all the possibilities to create periodic secondary structures. The absolute configurations can be regarded as the basic instruction set in the assembly language of the peptidic foldamer sequences, and an stereochemical patterning approach was established. We tested the SPA experimentally in terms of sequences with a novel backbone stereochemical pattern, giving an H14/16 helix and an H9-12 helix. These are de novo designed helices. Further evidence in connection with the relevance of the SPA is the two distorted structures with the swapped backbone pattern, because they do not form helical structures. Their secondary structure is loop-like.

Product Specifications
SKU :COC77801
AuthorIstvan M. Mandity
LanguageEnglish
BindingPaperback
Number of Pages80
Publishing Year2014-09-23T00:00:00.000
ISBN9783659589966
Edition1 st
Book TypeOrganic chemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
0 Review(s)