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Design of Quinazolones As Potential Novel Antibacterial Agents


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  • Product Description

This book reported the literature survey of the chemistry of benzoxazin compounds including the methods of synthesis and their reactivity. In this context, we reported herein the behavior of 4-(4-oxo-4H-3,1-benzoxazin-2-yl)phenyl-4-methyl benzene sulfonate towards some active reagents as a facile and convenient route to some heterocyclic derivatives containing a quinazolone and/or sulfonate moieties. The methods of synthesis and the synthetic mechanisms of the aforementioned reactions were well presented and the structures of these compounds were assessed by analytical and spectral data. This book evaluated the synthesized compounds as antimicrobial agents against Gram positive bacteria (Bacillus Thuringenesis) and Gram negative bacteria (Klebseilla Pneumonia) strains. The results revealed that most of obtainable compounds exhibited high activities compared with Septazole as reference drug.

Product Specifications
SKU :COC40558
AuthorAhmed El-Mekabaty Mohamed,Osman Habib and Hussein Hassan
Number of Pages104
Publishing Year5/31/2012
Edition1 st
Book TypeOrganic chemistry
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-02-08 00:00:00
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