Petroleum refinery is an industrial process plant where crude oil is processed and refined into more useful petroleum products, such as gasoline, diesel fuel, asphalt base, heating oil, kerosene, and liquefied petroleum gas, it consist of several units which have great importance such as Heat exchanger trains, Pre flash tower, Crude distillation tower and Vacuum distillation.It is important to size and design distillation tower properly and expertly to get desire products of petroleum with their required specifications. This report work is divided in to seven chapters. First three chapters discuss about introduction, history and main process which are carried out in refinery. Chapter four discuss important factors which have sound impact on distillation operation, chapter five discusses about the Designing of crude distillation tower for 6000 BPSD production. Chapter six and seven Discuss about selection of necessary equipments used in fuel refinery such as pumps, heat exchangers, valves etc. And lastly the utilities require for plant operation.