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Determination of Clarithromycin in Pure & Pharmaceutical Formulations

 

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  • Product Description
 

A simple and sensitive spectrophotometric method has been developed for the determination of clarithromycin in pure and commercial pharmaceutical formulations. The method involves formation of colored ion-associate complex of clarithromycin with bromothymol blue in acidic media (acetate buffer solution). The colored complex was extracted in chloroform which showed the optimum wavelength at 420 nm. Various conditions such as wavelength, acetate buffer pH, acetate buffer volume, bromothymol blue solution concentration and bromothymol blue solution volume were investigated. At the optimum conditions, the method has been applied for the determination of clarithromycin in commercial pharmaceutical formulations. The investigated spectrophotometric method has numerous advantages, for examples, the use of inexpensive chemicals, sensitivity and reproducibility and can be used as alternatives for routine analysis of clarithromycin.

Product Specifications
SKU :COC30373
AuthorWaqar Ahmad and Kashif Shahid
LanguageEnglish
BindingPaperback
Number of Pages64
Publishing Year11/19/2012
ISBN978-3659306662
Edition1 st
Book TypeMedicine
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-31 00:00:00
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