The issues of datum transformation of GPS coordinates from WGS84 to the Ghana War Office coordinate systems and vice versa are real, persistent and serious problem that requires pragmatic measures for solutions for geospatial and non-geospatial professionals in Ghana and around the world. These professionals in their day-to-day activities are challenged with the task of integrating geodetic information based on two different incompatible geodetic datums. The complexity of this incompatibility between different mapping systems or datums is also a general concern to those involved in the collection of natural resources data where projections and conversion between datums are required. Hence, there is much need to determine transformation parameters that will mathematically convert observed GPS based data to the national geodetic reference system in order to avoid discrepancies caused by the change of geodetic datum data from one geodetic datum to another. Therefore,this book provides the theoretical basis and practical methods for geospatial and non-geospatial professionals/students for GPS coordinate transformation parameters determination between the War Office and WGS84 system.