Diabetes is now considered as most common global metabolic disease affecting more than 150 million people worldwide. Diabetes is considered as a major health problem facing the world as life threatening disease. It is the seventh leading cause of death in the world. Diabetic foot problem is the major cause of hospital bed occupancy, so this research aimed to study the identification of bacteria isolated from diabetic foot infections. Also to determine the susceptibility of the various bacterial isolates to selected antibiotics commonly used in therapy of bacterial infections. Devitalized tissue provides a favourable environment for microbial growth and thus its removal will also reduce microbial load. Surgical debridement has been the mainstay of treatment of wounds of various etiologies. Due the current problems of antibiotic resistance and the difficulties in controlling MRSA (Methicillin Resistant Staphylococcus aureus) infection have led to increase interest in maggot therapy of wound healing. The research provides several practical recommendations which have been tested in Sudanese diabetics’ patients.