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Dietary Flavonoids and Risk of Breast Cancer and Childhood Leukemia

 

Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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  • Product Description
 

Numerous studies have demonstrated an inverse relationship between dietary flavonoid intake and cancer risk,which may be modified by polymorphisms in flavonoid metabolizing genes such as NQO1.The independent role of dietary flavonoids was explored in breast cancer and childhood leukemia (accounting for NQO1 genotype),using data from the LACE and NCCLS studies,respectively.High daidzein (soy) consumption after a breast cancer diagnosis was associated with a reduced risk of recurrence in postmenopausal women treated with tamoxifen.A significantly reduced risk of childhood leukemia was associated with mothers who consumed the most flavonoids during pregnancy.Carrying the NQO1*2 variant allele was not independently associated with the risk of childhood ALL or AML and there was no significant interaction with flavonoid intake.In a meta-analysis,NQO1*2 had no significant effect on risk of childhood leukemia overall but was associated with an increased risk in a subset of leukemia cases with MLL translocations. These results suggest that high flavonoid intake may be associated with a reduced risk of breast cancer and childhood leukemia.

Product Specifications
SKU :COC13080
AuthorNeela Guha
LanguageEnglish
BindingPaperback
Number of Pages124
Publishing Year12/28/2010
ISBN978-3639296556
Edition1st
Book TypeClinical & internal medicine
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-07-22 00:00:00