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Discovery of HIV-1 Integrase Inhibitors

 

Marketed By :  VDM Verlag Dr. Müller   Sold By :  Kamal Books International  
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  • Product Description
 

Highly active antiretroviral therapy (HAART) is the current treatment regimen for HIV/AIDS, a disease that has claimed millions worldwide. HAART is a cocktail that inhibits different stages of the viral life cycle targeting protease, reverse transcriptase, and often includes anti-fusion inhibitor enfurvitide. The addition of HIV-1 integrase (IN) inhibitor raltegravir to HAART reveals a decrease of the virus to near undetectable levels in treatment-experienced patients. Although these successes are encouraging for antiviral therapy, specific mutations resistant to raltegravir have also appeared. Drug resistant mutations is the inevitable signature of HIV with a merry-go-round history of antiviral drug development and viral evolution, highlighting the need to identify new leads for IN inhibition. Absent of a cellular

Product Specifications
SKU :COC38410
Country of ManufactureIndia
Product BrandVDM Verlag Dr. Müller
Product Packaging InfoBox
In The Box1 Piece
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