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DNA methylation during development in mammals


Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description

This book is focusing on dynamics of de-novo methylation in embryonic genes during development and tissue differentiation and its correlation with the expression of genes in laboratory mouse.DNA methylation is an epigenetic mark present on genomic DNA. Its key role lies in regulation of gene expression. During embryonic development, the gametic methylation is removed within the first few cleavage divisions, and for most genes a fresh wave of methylation occurs during post- implantation development, making DNA methylation an integral part of cellular differentiation and differential gene function. How does the fresh wave of methylation set in the genome is not well understood. Patterns of methylation of the genes studied are distinct from those DNA sequences which methylate pre- and post-implantation, both in terms of the timing and spreading.

Product Specifications
SKU :COC87352
AuthorManisha Sachan and Mamta Pamnani
Number of Pages96
Publishing Year2013-11-06T00:00:00.000
Edition1 st
Book TypeBiology, life sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00