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Doxorubicin Induced Cardiotoxicity: The Spice Retreat

 

Marketed By :  LAP LAMBERT Academic Publishing   Sold By :  Kamal Books International  
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  • Product Description
 

Doxorubicin/Adriamycin (Dox) is a powerful, well established and highly efficacious drug in the fight against many kinds of cancers like solid tumors, leukemia’s, soft tissue sarcoma, breast cancer, small cell carcinoma of the lung and esophageal carcinomas. But its clinical usefulness is still restricted due to its specific toxicities to cardiac tissues. Congestive heart failure, cardiomyopathy, and electrocardiographic changes were demonstrated after cumulative Dox administration.The possible mechanisms proposed for cardiotoxic effects of Doxorubicin include free radical induced myocardial injury, lipid peroxidation, mitochondria damage, decreased activity of Na, K-adenosine triphosphate, vasoactive amine release, impairment in myocardial adrenergic signaling/regulation and cellular toxicity. The present book will reveal the role of common spice on biochemical alterations and oxidative status against Doxorubicin/adriamycin induced cardiotoxicity.

Product Specifications
SKU :COC76745
AuthorSumeet Gullaiya and Swati Madan
LanguageEnglish
BindingPaperback
Number of Pages128
Publishing Year2014-03-17T00:00:00.000
ISBN9783659301148
Edition1 st
Book TypePre-clinical medicine: basic sciences
Country of ManufactureIndia
Product BrandLAP LAMBERT Academic Publishing
Product Packaging InfoBox
In The Box1 Piece
Product First Available On ClickOnCare.com2015-10-08 00:00:00
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